Melissa McCarthy Debuts Weight Loss Transformation During SNL Stint

The Bravo host detailed his health and fitness journey using an Ozempic-like drug.

"I did, this summer, lose a good chunk of weight by micro-dosing a GLP-1," the 57-year-old revealed in September 2025 during an episode of his SiriusXM Andy Cohen Live radio show. "I was really unhappy with my weight. My doctor and I talked about this last year, had recommended a GLP-1 a few times to not only address what I was feeling about my weight, but treat plaque in my arteries and high blood pressure. This is a medication that actually is beneficial to a lot of elements of health and I finally said 'yes.'"

"I have to say, it really helped me with cravings," he continued, "which I was having a very hard time with, and really forcing myself to be more disciplined with my diet and with working out."